منابع مشابه
Animal lectins as cell adhesion molecules.
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners. Focusing on two classes of lectins (selectins and galectins), it is evident that their functionality for mediation of adhesive contacts is becoming increasingly ...
متن کاملParasite Lectins: More than Adhesion Molecules?
Several studies demonstrate the involvement of lectins in the recognition of carbohydrates present on the surface of different kinds of pathogens [1-3], including parasites of the genus Leishmania [4,5]. The recognition often involves the modulation of the host immune response due to the activation of signaling pathways initiated by the stimulation of lectins present on the surface of cells fro...
متن کاملThe cadherins: cell-cell adhesion molecules controlling animal morphogenesis.
Cadherins are a family of glycoproteins involved in the Ca2+-dependent cell-cell adhesion mechanism which is detected in most kinds of tissues. Inhibition of the cadherin activity with antibodies induces dissociation of cell layers, indicating a fundamental importance of these molecules in maintaining the multicellular structure. Cadherins are divided into subclasses, including E-, N- and P-cad...
متن کاملCD44 cell adhesion molecules.
The CD44 proteins form a ubiquitously expressed family of cell surface adhesion molecules involved in cell-cell and cell-matrix interactions. The multiple protein isoforms are encoded by a single gene by alternative splicing and are further modified by a range of post-translational modifications. CD44 proteins are single chain molecules comprising an N-terminal extracellular domain, a membrane ...
متن کاملEndothelial Cell Adhesion Molecules
Endothelial adhesion molecules play an important role in the tissue recruitment of leukocytes in inflammatory conditions such as rheumatoid arthritis. We have investigated the effect of the antirheumatic drug gold sodium thiomalate on adhesion molecule protein and mRNA expression in cultured human endothelial cells. Gold sodium thiomalate inhibited cytokine (TNF, IL-1, IL-4)-stimulated expressi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cells Tissues Organs
سال: 1998
ISSN: 1422-6405,1422-6421
DOI: 10.1159/000046456